Ministry of Public Health sends the clinical manifestation of true sexual precosity of the civilization and diagnoses the basis

Ministry of Public Health sends the clinical manifestation of true sexual precosity of the civilization and diagnoses the basis
Sino-Singaporean network, December 17, a few days ago, Ministry of Public Health release about in official site their>Notice. And diagnoses the clinical manifestation of the sexual precosity according to carrying on clearly in " guide ". The full text follows:
Guide (tentative) of making a diagnosis in sexual precosity
First, definition
Sexual precosity (precocious puberty) Mean the boy was 9 years old ago, the girl presented the second sex character 8 years old ago. Divide for the centre (the releasing hormone dependence of gonadotropin) according to pathogenesis and clinical manifestation Sexual precosity and peripheral (the releasing hormone dependence of non- gonadotropin) Sexual precosity, called genuine sexual precosity and false sexual precosity respectively in the past. Centre sexual precosity (central precocious puberty, CPP) Ones that are similiar to with normal youthful development are hypothalamic - hypophysis - gonad axle (HPGA) Launch, ripe procedural course, until reproductive system being ripe; Namely by hypothalamic to secrete and release releasing hormone of gonadotropin (GnRH) ahead of time ,Activate hypophysis, secrete gonadotropin, enable gonad development and secrete sex hormone, thus in making, external genitalia development and the second sex character appear. Peripheral sexual precosity to because of, raise to adolescence level by various internal the intersection of and the intersection of steroid and the intersection of body and hormone that reason cause, so only second sex character is early now, do not have intact procedural course of sex development.
Second, cause of disease
(1) Centre sexual precosity.
1.Central nervous system organic disease, the following thalamus, hypophyseal tumour or other central nervous system pathological changes.
2.Transformed by the peripheral sexual precosity.
3.Ones that fail to find organic disease, are specially called the sending centre sexual precosity (idiopathic CPP, ICPP) .
4.The centre sexual precosity of incompleteness, it is a special type of CPP, the ones that meant the infant has the second sex character are early now, its controlling mechanism lies in being hypothalamic too - hypophysis - axis of gonad is mobilized, but its sex character develops and presents from the limit; Most common type getting simple the intersection of breast and early development, take place on girl under 2 year old, may because hypothalamic and the intersection of gonad and axle in physiology nature enliven the state, call " little adolescence " also .
The girl regards ICPP as manily, accounts for more than 80%-90% of CPP; But the boy is opposite, more than 80% are organic.
(2) Peripheral sexual precosity.
1.Classify according to the second sex character characteristic: Called the sexual precosity of the same sex when early second sex character now is the same as infant's original gender, called the opposite sex sexual precosity when being opposite to original gender.
2.Classification of common cause of disease
2.1 girls
(1)Sexual precosity of the same sex (the second sex character of the girl's) : See that unusual like McCune-Albright syndrome in the ovarian function of heredity, the ovary takes pathological change such as self-disciplining ovarian cyst in the location benignly, secrete renal gland cortex tumour or ovarian tumour, malposition of estrogen and secrete people chorion gonadotropin (HCG) Tumour and it is other for source take in estrogen.
(2)Opposite sex's sexual precosity (male second sex character) : See at the inborn renal gland cortex hyperplasia disease, secrete androgenic renal gland cortex tumour or ovarian tumour, and other source androgen is taken in etc..

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